Focal adhesion kinase mediates human leukocyte histocompatibility antigen class II-induced signaling in gingival fibroblasts

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Focal adhesion kinase (FAK) mediates human leukocyte histocompatibility antigen (HLA) class II-induced signaling in gingival fibroblasts

Short title: HLA II-induced signals in gingival fibroblasts. 1. Department of Patho-physiology Periodontal Science, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama, Japan 2. First Department of Pathology, Hyogo College of Medicine, Hyogo, Japan 3. Department of Allergy and Immunology, Saitama Medical School, Saitama, Japan 4. (current address) Depa...

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Human Leukocyte Antigen Class I and II Variants in Yemeni Patients with Chronic Renal Failure

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Soluble CD14 mediates lipopolysaccharide-induced intercellular adhesion molecule 1 expression in cultured human gingival fibroblasts.

Intercellular adhesion molecule 1 (ICAM-1) is involved in the accumulation and activation of leukocytes in inflammatory diseases such as periodontitis. As reported previously, ICAM-1 is up-regulated on cultured human gingival fibroblasts (HGF) by exposure to lipopolysaccharide (LPS), suggesting a specific LPS recognition mechanism. We therefore investigated the role of CD14, an LPS receptor, in...

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P-164: Human Leukocyte Antigen Class Ib and Pregnancy Success

Background: During pregnancy, the maternal immune system is in close contact with cells and tissue from the semiallogenic fetus .The Human Leucocyte Antigen (HLA) class Ib molecules, HLA-E, -F and -G, are expressed at the materno-fetal interface. Because of the apparent immunoregulatory functions of these proteins, they may be involved in successful acceptance of the semi-allogenic fetus during...

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Background: Endometrial remodeling occurs during each menstrual cycle in women. Reports have shown that, in a variety of cell types, processes such as proliferation, signaling complex formation and extra cellular matrix remodeling require a cytoplasmic tyrosine kinase, focal adhesion kinase (FAK). The present study has focused on the expression pattern of FAK in human endometrium during the men...

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ژورنال

عنوان ژورنال: Journal of Periodontal Research

سال: 2007

ISSN: 0022-3484,1600-0765

DOI: 10.1111/j.1600-0765.2007.00985.x